Safety data sheet
Standardized safety protocols and material specifications for professional use.
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Purity verified via High-Performance Liquid Chromatography (HPLC) for #myo-adamax-10mg
Adamax (10mg)
High >98% Purity
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Scientific Background
Adamax is an advanced adamantane-modified version of Semax, a synthetic heptapeptide derived from the ACTH(4–10) fragment. The adamantane group increases lipophilicity, enzymatic stability, and blood-brain barrier penetration, potentially leading to stronger and longer-lasting effects compared to standard Semax.
Semax itself is widely studied for its nootropic and neuroprotective properties, including boosting brain-derived neurotrophic factor (BDNF) and TrkB receptor expression in the hippocampus, balancing dopamine/serotonin systems, and supporting neuroplasticity.
Preclinical research on Semax shows increased BDNF protein levels, TrkB signaling activation, and better neuronal survival under stress or reduced blood flow conditions. Adamax builds on this foundation with structural improvements aimed at amplified cognitive enhancement, memory support, and brain protection in experimental models.
Adamax targets neurotrophic pathways similar to Semax, promoting BDNF upregulation, TrkB receptor activation, and downstream routes like cAMP/CREB for synaptic plasticity and neuronal adaptation. The adamantane modification is studied for 2–3 times greater potency in cognitive and endurance outcomes due to better penetration and half-life.
As an investigational compound, Adamax is not approved for therapeutic use and is provided strictly for research purposes into cognitive function, neuroplasticity, and brain health.
Intended Research Use
- Cognitive enhancement via BDNF/TrkB upregulation in hippocampal models
- Neuroprotection in ischemia, oxidative stress, and reduced blood flow models
- Mood and stress resilience through dopamine/serotonin modulation
- Neuroplasticity and synaptic connectivity research
- Comparison of adamantane-modified analogs vs. standard Semax for BBB penetration and potency
menu_bookScientific Publications
Neurosci Lett (2006)
Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/16805748/
Neurosci Lett (2006)
Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/16934747/
Neurosci Behav Physiol (2009)
Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/19862692/
Neurosci Behav Physiol (2008)
Comparison of the temporary dynamics of NGF and BDNF gene expression in rat hippocampus, frontal cortex, and retina under Semax action
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/18720600/
Neurosci Behav Physiol (2006)
Neuroprotective effects of Semax in cerebral ischemia models
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/17100392/
J Pept Sci (2012)
Adamantane modifications in peptide design for enhanced stability and CNS penetration
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/22587715/
Eur J Med Chem (2018)
Adamantane conjugates and structural analogs for improved pharmacokinetics
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/29980247/
Neurosci Behav Physiol (2021)
Semax in ischemia-reperfusion models
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/34575984/
FOR RESEARCH USE ONLY. This product is intended for laboratory research purposes only and is not for human consumption, medical, or diagnostic use.
Possible stacks with other peptides
Synergistic combinations for enhanced research outcomes
Adamax is commonly studied alongside other nootropic, neuroprotective, and repair-focused peptides to explore multi-pathway effects on BDNF signalling, neuroplasticity, and cognitive performance.
Semax (10mg vial)
arrow_forwardmyo-semax-10mg
The parent compound of Adamax. Stacking both is studied for amplified nootropic and anxiolytic synergy, comparing structural variants of the same ACTH(4–10) derivative.
Selank (10mg vial)
arrow_forwardmyo-selank-10mg
A GABAergic anxiolytic peptide. Combined with Adamax to investigate complementary effects on mood, stress resilience, and focus through different receptor systems.
Cerebrolysin (60mg vial)
arrow_forwardmyo-cerebrolysin-60mg
A neurotrophic factor mixture studied for neuroplasticity and BDNF support. Paired with Adamax in neuroprotection and cognitive enhancement models.
BPC-157 (5mg vial)
arrow_forwardmyo-bpc-157-5mg
Combined with Adamax in models exploring parallel tissue repair and brain recovery, leveraging BPC-157's cytoprotective and angiogenic properties alongside Adamax's neurotrophic effects.
NAD+ (500mg vial)
arrow_forwardmyo-nad-plus-500mg
NAD+ precursors complement BDNF-mediated energy and repair pathways, supporting mitochondrial function and cellular resilience alongside Adamax's neuroprotective activity.
Cycling Note: Standard Adamax cycles run 8–12 weeks with an equal off-period. Stacked peptides with different half-lives (e.g., Cerebrolysin, NAD+) may follow independent cycling schedules.