Safety data sheet
Standardized safety protocols and material specifications for professional use.
Certificate of Analysis
Purity verified via High-Performance Liquid Chromatography (HPLC) for #myo-nad-plus-500mg
NAD+ (500mg)
Ultra High >99.5% Purity
Authorized Resellers
Available through our trusted partners
123peptide.com
Netherlands · Europe
local_shipping2-3 Business Days
Depeptidenwinkel.com
Netherlands · Europe
local_shipping2-3 Business Days
Scientific Background
Nicotinamide Adenine Dinucleotide (NAD+) is an essential coenzyme found in every living cell. It functions as a critical electron carrier in cellular respiration, cycling between its oxidised (NAD+) and reduced (NADH) forms to facilitate the electron transport chain and ATP synthesis in mitochondria. Beyond energy metabolism, NAD+ serves as a substrate for key regulatory enzymes including sirtuins (SIRT1–7) and PARPs — enzymes involved in DNA repair, gene expression, and cellular stress responses.
NAD+ levels decline progressively with age and metabolic dysfunction, a phenomenon linked to reduced mitochondrial efficiency, impaired DNA repair capacity, and increased susceptibility to oxidative stress and age-related diseases. Preclinical research in animal models has demonstrated that NAD+ replenishment can restore mitochondrial function, improve metabolic parameters, and extend healthspan.
Subcutaneous NAD+ administration bypasses the gastrointestinal degradation that limits oral bioavailability, offering more direct systemic delivery. Research protocols explore titrated subcutaneous dosing as a maintenance approach following initial IV loading, making the 500 mg vial suitable for standard-dose protocols.
Intended Research Use
- Mitochondrial function and cellular energy metabolism research
- Sirtuin (SIRT1–7) activation and longevity pathway studies
- DNA repair mechanism research (PARP enzyme substrate)
- Age-related metabolic decline and healthspan models
- Oxidative stress and redox biology studies
- Neuroprotection and cognitive function research
menu_bookScientific Publications
Cell Metabolism (2018)
NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/29432159/
Nature Communications (2018)
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/29643480/
Molecular and Cellular Endocrinology (2017)
NAD and the aging process: Role in life, death and everything in between
open_in_newhttps://pubmed.ncbi.nlm.nih.gov/27825999/
FOR RESEARCH USE ONLY. This product is intended for laboratory research purposes only and is not for human consumption, medical, or diagnostic use.
Possible stacks with other peptides
Synergistic combinations for enhanced research outcomes
NAD+ combines effectively with mitochondrial and longevity-focused compounds for comprehensive cellular energy and healthspan research.
SS-31 (Elamipretide) (10mg vial)
arrow_forwardmyo-ss-31-elamipretide-10mg
Mitochondrial protection pairing — SS-31 directly protects the inner mitochondrial membrane from oxidative damage while NAD+ fuels the electron transport chain, creating synergistic mitochondrial support.
MOTS-C (10mg vial)
arrow_forwardmyo-mots-c-10mg
Mitochondrial signalling synergy — MOTS-C activates AMPK and nuclear gene programmes for metabolic adaptation while NAD+ provides the coenzyme fuel for mitochondrial energy production.
GLOW Blend (70mg vial)
arrow_forwardmyo-glow-blend-70mg
Regenerative combination — GLOW Blend's BPC-157, TB-500, and GHK-Cu tissue repair effects are energetically supported by NAD+ replenishment, creating a comprehensive cellular restoration protocol.
NAD+ 1000mg (1000mg vial)
arrow_forwardmyo-nad-plus-1000mg
Higher-dose NAD+ variant for maintenance protocols — the next-step format after initial 500mg tolerance assessment.
Cycling Note: NAD+ protocols typically run 8–16 weeks. Rest intervals of 2–4 weeks allow assessment of sustained NAD+ level improvements. Monitor energy and cognitive markers for protocol response.
