Selank (10mg)

Selank is a synthetic heptapeptide analog of tuftsin (Thr-Lys-Pro-Arg) extended with a Pro-Gly-Pro C-terminal sequence that significantly enhances its stability and CNS penetration. Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank was specifically engineered to deliver anxiolytic and nootropic effects comparable to benzodiazepines without the sedation, dependence risk, or cognitive impairment associated with GABAergic drugs.

Selank's mechanisms are multi-target: it modulates GABAergic neurotransmission, upregulates BDNF expression in the hippocampus, balances serotonin and dopamine levels, and regulates enkephalin metabolism and interleukin-6 (IL-6) expression. This combination produces anxiolytic, anti-asthenic, and mild cognitive-enhancing effects without sedation — a profile consistently described as "benzodiazepine-like calm without the downsides."

Russian clinical trials demonstrated Selank's efficacy in generalised anxiety disorder and neurasthenia models, with favourable tolerability and no dependence liability. Its immunomodulatory properties — particularly IL-6 regulation — add an additional layer of research relevance in stress-immune axis studies. Compared to Semax (more cognitively stimulating) and Adamax (stronger BDNF/nootropic but more activating), Selank is positioned as the gentler, mood-stabilising option in the Russian nootropic peptide family.